Grover disease - Maladie De Grover
La Maladie de Grover (Grover disease) est une affection qui apparaît soudain sous forme de taches rouges qui démangent sur le tronc, le plus souvent chez les hommes âgés.
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ReferencesGrover disease (dermatose acantholytique transitoire) est une éruption cutanée qui se manifeste par des papules remplies de liquide sur le tronc supérieur, principalement chez les hommes blancs d’âge moyen. Elle démange souvent mais est de courte durée. Quatre types différents de modifications tissulaires ont été décrits dans la Grover disease, et elle a été associée à diverses pathologies, notamment les cancers du sang. La maladie peut être difficile à diagnostiquer et à traiter, car elle a tendance à apparaître et à disparaître spontanément. Étant donné que la Grover disease a été fréquemment associée à d’autres affections cutanées, tant dermatologiques que non dermatologiques, il est essentiel d’exclure les troubles concomitants, y compris les tumeurs malignes hématopoïétiques.
Grover disease, also known as transient acantholytic dermatosis, is a rash that appears as bumps filled with fluid on the upper body, mainly in older white men. It's often itchy but doesn't last long. There are 4 different patterns of tissue changes in Grover disease, and it has been linked to various illnesses, like blood cancers. It can be hard to track and treat because it tends to come and go on its own. Because Grover disease has been associated frequently with other dermatologic and nondermatologic skin conditions, to rule out other concomitant disorders, including hematopoietic malignancies is essential.
Grover disease, also known as transient acantholytic dermatosis, is a rash that appears as bumps filled with fluid on the upper body, mainly in older white men. It's often itchy but doesn't last long. There are 4 different patterns of tissue changes in Grover disease, and it has been linked to various illnesses, like blood cancers. It can be hard to track and treat because it tends to come and go on its own. Because Grover disease has been associated frequently with other dermatologic and nondermatologic skin conditions, to rule out other concomitant disorders, including hematopoietic malignancies is essential.
Ce rapport porte sur un cas rare de Grover's disease chez un homme blanc de 80 ans, qui présentait une éruption cutanée sur la poitrine depuis trois à quatre mois. Il a des antécédents d'hypertension artérielle, d'hypercholestérolémie, d'arthrite du genou, de reflux gastro‑œsophagien chronique, de tachycardie, d'antécédents de cancer de la prostate et du syndrome des jambes sans repos. Au départ, il présentait une éruption rouge, bosselée et prurigineuse, principalement sur le haut du corps. Malgré l'utilisation de diverses crèmes et lotions, ses symptômes se sont peu améliorés. Après consultation d'un dermatologue et réalisation d'une biopsie cutanée, le diagnostic de Grover's disease a été confirmé. Il a alors été traité avec une crème à base de stéroïde pendant deux semaines.
This case report details a rare case of Grover's disease in an 80-year-old Caucasian male complaining of a rash across his chest over the last three to four months. The patient has a past medical history of essential hypertension, hyperlipidemia, osteoarthritis of the knee, chronic gastroesophageal reflux disease (GERD), supraventricular tachycardia, status post prostate cancer, and restless legs syndrome. During his initial evaluation, he was found to have a pruritic, erythematous, papular rash most notably along his upper trunk and chest. The patient utilized multiple lotions, emollients, and anti-itch creams with minimal relief of his symptoms and presentation. Following a referral to Dermatology, a biopsy of the rash was conducted, which revealed intraepidermal acantholysis, the hallmark finding for a diagnosis of Grover's disease. Subsequently, he was treated with a topical triamcinolone acetonide 0.1% cream for 14 days.
This case report details a rare case of Grover's disease in an 80-year-old Caucasian male complaining of a rash across his chest over the last three to four months. The patient has a past medical history of essential hypertension, hyperlipidemia, osteoarthritis of the knee, chronic gastroesophageal reflux disease (GERD), supraventricular tachycardia, status post prostate cancer, and restless legs syndrome. During his initial evaluation, he was found to have a pruritic, erythematous, papular rash most notably along his upper trunk and chest. The patient utilized multiple lotions, emollients, and anti-itch creams with minimal relief of his symptoms and presentation. Following a referral to Dermatology, a biopsy of the rash was conducted, which revealed intraepidermal acantholysis, the hallmark finding for a diagnosis of Grover's disease. Subsequently, he was treated with a topical triamcinolone acetonide 0.1% cream for 14 days.
